Lose More Weight with Semaglutide & Tirzepatide.

It’s true. Semaglutide and Tirzepatide are two of the most effective weight loss injections to come onto the market in many years. Both drugs are FDA-approved and backed by years of research and work by mimicking a natural peptide in the body that tells the brain that you are full. Both medications were originally developed and approved for individuals with Type II Diabetes because they help to control blood sugar, and are being marketed under the brand names of Ozempic, Wegovy (Semaglutide) and Mounjaro (Tirzepatide) by the pharmaceutical companies that developed them.

That is important all by itself, but clinical trials found that they drastically reduced hunger in most individuals who took them and helped them achieve fast weight loss. Participants lost excess body fat – including abdominal fat – and increased the proportion of lean body mass (or the amount of weight someone carries that is not body fat). In February 2021, researchers showed that patients who injected Semaglutide weekly and made lifestyle changes lost about 33.7 lbs versus 5.7 pounds in those who didn’t use the drug. (1)

Tirzepatide is an even newer once-weekly injection that has been shown to help people lose weight fast. A phase 3 clinical trial found that regular use of this new drug helped patients lose 22.5% of their body weight on average, or about 52 pounds in 28 weeks. Because of these stunning results, the FDA fast-tracked the medications for approval for weight loss without diabetes.

Although it’s important that any weight loss drug be used with a healthy diet and exercise, the new medications help make fast weight loss a reality for many who have struggled or failed in the past. Dr. Robert Gabbay, chief scientific and medical officer for the American Diabetes Association, told USAToday.com that “the study results are a game-changing level of weight loss typically unheard of without weight loss surgery”. (2)

The new medications reduce your appetite and crush cravings almost instantly.

Both Semaglutide and Tirzepatide are what are called “glucagon-like peptide 1 (GLP-1) receptor agonists”. This means they act like a certain natural peptide in your body that tells your brain that your stomach is full. They work by increasing lipolysis (fat utilization for fuel) and metabolic rate (metabolism) and decreasing appetite, fat storage and rate of digestion. Many patients also experience improvements in risk factors for heart disease, blood sugar levels and quality of life. Both medications are designed to be taken by painless injection.

Tirzepatide, the newest medication, is a GLP-1 like Semaglutide, but it also contains a “glucose-dependent insulinotropic polypeptide (GIP) receptor agonist”. This means that it has a dual action that can be even more effective at promoting weight loss for certain individuals. In a clinical trial of 3,731 patients, Tirzepatide was particularly effective in reducing abdominal fat and triglycerides. (3) (4).

Who can get GLP-1 weight loss medications?

Overweight and obese individuals generally qualify for use of these medications, but medical screening is important so that a professional can identify any personal health risks and monitor your progress, especially if you take other medications that regulate blood sugar.

Brand name GLP-1 medications can be extremely expensive and fewer and fewer insurance companies will cover the expense. In addition, there have been shortages caused by the sudden explosion in demand. Generic versions are available and can be much more affordable. They are made by fully licensed compounding pharmacies at a lower cost.

Experts can help minimize side effects as you lose weight fast.

To get maximum results, work with professionals who understand the prescribing process, can provide the best food plan to use with Semaglutide and Tirzepatide and help minimize side effects through proper dosing. Having professional support can also help prevent some of the reported concerns about losing too much muscle while losing weight fast: goal setting, tools to help protect your lean muscle, and guidance through the weight loss process can help you look and feel your best when you reach your goal. Plus, the right weight loss clinic can customize a Maintenance Plan so you keep the weight off for the long term.

Tips to look great and keep the weight off.

If you’ve tried other things to lose weight and stubborn weight gain is still impacting your life, reach out to our medically monitored weight loss clinic to see if one of these medications could be right for you. We can provide the best weight loss program, a healthy low-carb meal plan, nutrition coaching, Vitamin B12 or lipotropic injections to help boost results and protein bars/ shakes/snacks to help protect your muscles, so you look and feel great – no matter where you live. Check out our affordable GLP-1 plans.

Click here for more information and a FREE CONSULTATION in-clinic, via zoom or by phone.

Written by Susan Malzone, Director of LivLight Weight Loss

Works Cited

  1. Ghusn W, De la Rosa A, Sacoto D, et al. Weight Loss Outcomes Associated With Semaglutide Treatment for Patients With Overweight or Obesity. JAMA Netw Open. 2022
  2. Diabetes drug helps patients lose never-before-seen amounts of weight, study shows. A new study of the type 2 diabetes drug tirzepatide found it also resulted in dramatic weight loss, offering hope for those struggling with obesity. Ucom Weintraub, Karen. June 4, 2022
  3. Rizvi AA, Rizzo M. The Emerging Role of Dual GLP-1 and GIP Receptor Agonists in Glycemic Management and Cardiovascular Risk Reduction. Diabetes Metab Syndr Obes. 2022 Apr 5
  4. Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, Kiyosue A, Zhang S, Liu B, Bunck MC, Stefanski A; SURMOUNT-1 Investigators. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med. 2022 Jul 21